The Efficiency of Using Mirror Imaged Topography in Fellow Eyes Analyses of Pentacam HR Data

Purpose: To investigate the effectiveness of flipping left corneas topography and analysethem quantitively along with fellow right based on assumption that they are mirror images each other. Methods: The study involved scanning both eyes 177 healthy participants (aged 35.3 ± 15.8) 75 keratoconic 33.9 17.8). Clinical tomography data were collected for using Pentacam HR processed by a fully automated custom-built MATLAB code. For every case, eye was used as datum fixed surface while cornea flipped around in superior–inferior direction. In this position, root-mean-squared difference (RMS) between initially determined anterior posterior corneal surfaces. Next, iterative closest point transformation algorithm applied three-dimensional to allow translate rotate, minimising it surface. Then, RMS differences recalculated compared. Results: A comparison dioptric powers showed significant KC groups (p < 0.001). surfaces 0.6 0.4 D among group 4.1 2.3 group. After transforming corneas, recorded 0.5 0.3 2.4 2 groups, respectively. Conclusions: Although highly related their clinical parameters, should be treated care when one is other an optic-related research analysis where translation might needed. KC, asymmetric disease, observed portion asymmetry due apex shift interfering image acquisition. Therefore, rotation results fairer corneas.